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Conventional HRT and the Risk of Breast Cancer

The following is a list of articles and abstracts that address the risk of breast cancer with conventional hormone replacement therapy. The synthetic chemical, progestin, is often used as part of hormone replacement therapy and is thought to be the major culprit in the increased incidence of breast cancer.

Some of the following studies show a slight increase in the incidence of breast cancer with estrogen alone, others do not (even with up to fifteen years of use).

Estrogen versus Estrogen plus Progestin

Table 2

Hormone Replacement Therapy, Risks and Benefits

The WHI Estrogen-Alone Trial

Million Women’s Study

The following review of ‘Post menopausal Hormone Replacement Therapy’ explains the benefits and 
risks of conventional HRT which includes Progestins.